• Users Online: 5521
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
CASE REPORT
Year : 2017  |  Volume : 3  |  Issue : 2  |  Page : 88-90

Long-term effects of childhood management of retinoblastoma using chemo-radiotherapy on dental tissues: Literature review and case report


Department of Pedodontics and Preventive Dentistry, D.Y. Patil University, School of Dentistry, Nerul, Maharashtra, India

Correspondence Address:
Dr. Uma B Dixit
Department of Pedodontics and Preventive Dentistry, D Y Patil University School of Dentistry, Nerul - 400 706, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijohr.ijohr_38_17

Rights and Permissions

Retinoblastoma is the most common intraocular neoplasm of childhood which is caused by a defective RB1 gene. It is detected early in life by clinical presentation including leukocoria, strabismus, glaucoma, poor visual tracking, and inflammation among others. Antineoplastic therapy that children with childhood malignancies are submitted to, have long-term effects on various tissues in the body. With timely treatment, the 5 years survival rate for retinoblastoma is reported to be 99%. Dental anomalies commonly seen in these children are characterized by disturbances in shape, size, number, and mineralization in permanent teeth. The purpose of this case report is to present long-term effects of chemotherapy and radiotherapy on dental development in a patient treated for retinoblastoma in childhood and discuss its pathogenesis. Early diagnosis of presence and severity of dental anomalies will help the dentist to plan and implement an appropriate course of dental treatment to make the survivor child's life as normal as possible.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed4739    
    Printed393    
    Emailed0    
    PDF Downloaded65    
    Comments [Add]    

Recommend this journal